Skip to main content
NUTRITION 2026 Main banner

(OR25-05-26) Associations of Dietary Patterns With Cardiometabolic Risk Factors in Taiwanese Middle-Aged Women

Tuesday, July 28, 2026
9:18 AM - 9:30 AM ET
Location: Maryland Ballroom D

    Presenting Author(s)

  • JC

    Jane C.-J. D. Chao

    Taipei Medical University
    Taipei, Taipei, Taiwan (Republic of China)

    Disclosure information not submitted.

    • Co-Author(s)

  • Duong Phuc Phan, BS (he/him/his)

    master's student
    Taipei Medical University
    Taipei, Taipei, Taiwan (Republic of China)

    • Co-Author(s)

  • CH

    Chien-Yeh Hsu

    National Taipei University of Nursing and Health Sciences, Taipei, Taiwan (Republic of China)

Disclosure(s):
Duong Phuc Phan, BS: No relevant financial relationship(s) with ineligible companies to disclose.
Objectives: Middle-aged women could increase the risk of adverse metabolic outcomes and chronic diseases due to estrogen insufficiency or deficiency. We aimed to derive a cardiometabolic risk-driven dietary pattern (DP) using reduced rank regression and examine the associations with cardiometabolic risk factors among Taiwanese middle-aged women.

Methods: A cross-sectional study of 25,715 middle-aged women (40-60 years) from a health examination database was analyzed, and a reduced rank regression-derived DP was extracted from food frequency questionnaire using waist circumference, systolic/diastolic blood pressure, log-C-reactive protein, and log-fasting blood glucose as core responses. Multivariable linear and logistic regression, adjusted for sociodemographic and lifestyle factors, were used to evaluate the associations of the DP score with atherogenic index of plasma (AIP), triglyceride-glucose (TyG) index, central obesity, hypertension, impaired fasting glucose, and diabetes mellitus.

Results: The cardiometabolic risk-driven DP was characterized by higher processed/pickled foods, meat, fried foods, organ meats, and sauces, but lower sweet bakery products, legumes/soy products, and fruits. The cardiometabolic risk-driven DP score was positively associated with AIP (+0.022 unit per 1-SD) and TyG index (+0.048 unit per 1-SD). Furthermore, the women highly adherent to a cardiometabolic risk-driven DP (Q4 vs Q1 for DP score) significantly elevated the odds of central obesity (OR=2.33, 95% CI: 2.10-2.59), hypertension (OR=1.21, 95% CI: 1.11-1.32), impaired fasting glucose (OR=1.64, 95% CI: 1.52-1.77), and diabetes mellitus (OR=2.74, 95% CI: 2.20-3.41).

Conclusions: The cardiometabolic risk-driven DP, rich in processed/fried foods, meat, condiments, and organ meats, is associated with elevated AIP and TyG index, and higher odds of central obesity, hypertension, impaired fasting glucose, and diabetes mellitus in middle-aged women.

Funding Sources: Supported by the National Science and Technology Council, Taiwan (grant no. NSTC 114-2320-B-038-020)